HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 70377373, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1-(2-Chloroethyl)pyrrolidine | HCID 81669 | — |
| Reactant | 79258-51-8 | HCID 70377361 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 70377373 | HCID 70377373 | 61.4% |
Reaction Steps
2.72 g (8 mmoles) of (E)-1,2-diphenyl-3,3,3-trifluoro-1-(4-hydroxyphenyl)-propene, prepared as described in Example 26, are reacted in xylene with sodium hydride and then with 2-chloroethyl-pyrrolidine as described in Example 26. The product is crystallized from hexane. 2.15 g (61.4%) of the desired compound are obtained; m.p.: 84.5°-86° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04806685 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-30fbab3365a44ad6983f37292a5db494 |
| Source note | uspto-grants-1989_02 |