Hydrochloric Acid → HCID 14350503, compound

HRID 1382715Notes

Reaction equation

HRID 1382715 reaction equation
C[O:2][C:3]1[C:11]2[N:10]=[C:9]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[NH:8][C:7]=2[C:6]([O:18]C)=[CH:5][CH:4]=1.[Cl-].[Al+3].[Cl-].[Cl-].Cl>C1(C)C=CC=CC=1>[C:12]1([C:9]2[NH:10][C:11]3[C:3]([OH:2])=[CH:4][CH:5]=[C:6]([OH:18])[C:7]=3[N:8]=2)[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 6451240Aluminum(III) ChlorideHCID 14350501HCID 14350501, compound

Product 1

HCID 14350503HCID 14350503, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A 2.54 g portion of 4,7-dimethoxy-2-phenyl-1H-benzimidazole and 3.96 g of aluminum chloride in 125 ml of toluene were refluxed for 2 hours, then cooled and poured over cold dilute hydrochloric acid in ice. This mixture was stirred 0.5 hour, then the solid was collected, washed with water and dried, giving 2.0 g of the desired product, mp>280° C. (dec.).

Workup

  1. temperaturecooled
  2. customthe solid was collected
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-1ba715dbc1b54850a43f9eca280a3d0c
Source dataset
uspto-grants-1989_02
Patent number
US04808586

Reaction notes

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