HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 178481359, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 3-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3-oxopropanenitrile | HCID 2363689 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178481359 | HCID 178481359 | 91% |
Reaction Steps
1.21 g of 6-amino-5-(2-cyanoacetyl)-1,3-dimethyluracil and 2.90 g of sodium carbonate were added to 20 ml of water, and the solution was heated under reflux for 1 hr. After cooling, the precipitate was separated from the solution by filtration to give 1.09 g of 7-amino-5-hydroxy-1,3dimethylpyrido[2,3-d]pyrimidine-2,4-dione (Compound 18).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04808587 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-38c1d13621994b26a4e3470289652e16 |
| Source note | uspto-grants-1989_02 |