HCID 14372129, compound → HCID 14372146, compound

HRID 1382989Notes

Reaction equation

HRID 1382989 reaction equation
[S:1]([C:5]1[O:13][C:12]2[CH:11]=[CH:10][N:9]=[C:8]([O:14]C)[C:7]=2[CH:6]=1)(=[O:4])(=[O:3])[NH2:2]>Cl>[S:1]([C:5]1[O:13][C:12]2[CH:11]=[CH:10][NH:9][C:8](=[O:14])[C:7]=2[CH:6]=1)(=[O:3])(=[O:4])[NH2:2]

Participants

3

Reactant 1

HCID 14372129HCID 14372129, compound

Product 1

HCID 14372146HCID 14372146, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Conditions

Temperature
100 °C

Procedure

Alternate Procedure: A suspension of 2-sulfamoyl-4-methoxyfuro[3,2-c]pyridine (0.75 g, 3.3 mmol) in 10% aqueous hydrochloric acid (40 ml) was heated at 100° C. for 41/2 hours. Upon cooling, the product precipitated and was collected by filtration, washed with ethanol and diethyl ether to give 0.53 g (76% yield), m.p. 286°-289° C.

Workup

  1. temperatureUpon cooling
  2. customthe product precipitated
  3. filtrationwas collected by filtration
  4. washwashed with ethanol and diethyl ether
  5. customto give 0.53 g (76% yield), m.p. 286°-289° C.

Sources & evidence

ORD record
ord-15a743b8f9f34950ab9a807d78b7956e
Source dataset
uspto-grants-1989_02
Patent number
US04808595

Reaction notes

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