HCID 12237176, compound → HCID 14372148, compound

HRID 1383000Notes

Reaction equation

HRID 1383000 reaction equation
[Cl:1][C:2]1[C:7]2[CH:8]=[CH:9][O:10][C:6]=2[CH:5]=[C:4](C)[N:3]=1.[CH3:12]C1C2OC=CC=2C(=O)NC=1.CC1NC(=O)C2C=COC=2C=1>>[Cl:1][C:2]1[C:7]2[CH:8]=[CH:9][O:10][C:6]=2[C:5]([CH3:12])=[CH:4][N:3]=1

Participants

4

Reactant 3

HCID 12237176HCID 12237176, compoundHCID 122371844-chloro-6-methylfuro[3,2-c]pyridineHCID 14372147HCID 14372147, compound

Product 1

HCID 14372148HCID 14372148, compound

Procedure

The title compound was prepared according to the procedure described for 4-chloro-6-methylfuro[3,2-c]pyridine (Example 12, Step B) except 7-methylfuro[3,2-c]pyridin-4-(5H)-one was substituted for 6-methylfuro[3,2-c]pyridin-4-(5H)-one. Title compound was obtained in 98% crude yield and used as is. A portion was crystallized from cold diethyl ether for microanalysis, mp. 51.5°-53° C.

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-1c409d913b1d489db360b8fae7b353fe
Source dataset
uspto-grants-1989_02
Patent number
US04808595

Reaction notes

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