Lithium Hydroxide → 4-[[[5 (2-Propylphenoxy)pentyl]thio]methyl]-1,3-oxathiolane-2,2-dipropanoic acid

HRID 1383140Notes

Reaction equation

HRID 1383140 reaction equation
[CH2:1]([C:4]1[CH:36]=[CH:35][CH:34]=[CH:33][C:5]=1[O:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][S:12][CH2:13][CH:14]1[CH2:18][O:17][C:16]([CH2:26][CH2:27][C:28]([O:30]CC)=[O:29])([CH2:19][CH2:20][C:21]([O:23]CC)=[O:22])[S:15]1)[CH2:2][CH3:3].[OH-].[Li+]>>[CH2:1]([C:4]1[CH:36]=[CH:35][CH:34]=[CH:33][C:5]=1[O:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][S:12][CH2:13][CH:14]1[CH2:18][O:17][C:16]([CH2:19][CH2:20][C:21]([OH:23])=[O:22])([CH2:26][CH2:27][C:28]([OH:30])=[O:29])[S:15]1)[CH2:2][CH3:3]

Participants

3

Reactant 2

HCID 3939Lithium HydroxideHCID 14405892Diethyl 4-[[[5 (2-propylphenoxy)pentyl]thio]methyl]-1,3-oxathiolane-2,2-dipropanoate

Product 1

HCID 144058934-[[[5 (2-Propylphenoxy)pentyl]thio]methyl]-1,3-oxathiolane-2,2-dipropanoic acid

Procedure

The title compound was prepared according to the procedure of Example 3 using the ester produced in Example 8 (0.80 g, 0.0015 mol) and aqueous lithium hydroxide solution (2 M, 3.0 ml). The product, 0.78 g (89%), was obtained as an oil.

Workup

  1. customThe product, 0.78 g (89%), was obtained as an oil

Sources & evidence

ORD record
ord-223084a2703a465287898caa9a2d1ace
Source dataset
uspto-grants-1989_02
Patent number
US04808729

Reaction notes

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