Diethanolamine → HCID 70116843, compound

HRID 1383243Notes

Reaction equation

HRID 1383243 reaction equation
[OH:1][N:2]1[C:7]([CH3:9])([CH3:8])[CH2:6][CH:5]([O:10][CH2:11][CH:12]2[O:14][CH2:13]2)[CH2:4][C:3]1([CH3:16])[CH3:15].[NH:17]([CH2:21][CH2:22][OH:23])[CH2:18][CH2:19][OH:20]>O>[OH:1][N:2]1[C:7]([CH3:9])([CH3:8])[CH2:6][CH:5]([O:10][CH2:11][CH:12]([OH:14])[CH2:13][N:17]([CH2:21][CH2:22][OH:23])[CH2:18][CH2:19][OH:20])[CH2:4][C:3]1([CH3:16])[CH3:15]

Participants

4

Reactant 2

HCID 8113DiethanolamineHCID 3662321HCID 3662321, compound

Product 1

HCID 70116843HCID 70116843, compoundYield 29.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 2.28 g (0.01 mol) of 1-oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine and 1.05 g (0.01 mol) of diethanolamine in 25 mL of water is stirred at ambient temperature for 16 hours. The solution is then extracted with methylene chloride. The methylene chloride extract is dried over anhydrous magnesium sulfate, filter and concentrated. The crude reaction product is purified by column chromatography to afford 1.0 g of the title compound as a red oil.

Workup

  1. extractionThe solution is then extracted with methylene chloride
  2. extractionThe methylene chloride extract
  3. dry with materialis dried over anhydrous magnesium sulfate
  4. filtrationfilter
  5. concentrationconcentrated
  6. customThe crude reaction product
  7. customis purified by column chromatography

Sources & evidence

ORD record
ord-abc415fa4365433faddbdc5fd0cfe9e1
Source dataset
uspto-grants-2001_07
Patent number
US06254724B1

Reaction notes

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