HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dimethylchlorobenzene → 1-(Bromomethyl)-3-chloro-5-methylbenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dimethylchlorobenzene | HCID 32887 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Catalyst | Azobisisobutyronitrile | HCID 6547 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 1-(Bromomethyl)-3-chloro-5-methylbenzene | HCID 12375549 | 81.5% |
Reaction Steps
A solution of 5-chloro-m-xylene (14.06 g; 0.1 mol), NBS (17.8 g; 0.1 mol) and AIBN (1.1 g; 6.7 mmol) in CCl4 was refluxed for two hours. The resultant mixture was cooled, and the solid material formed was removed by filtration. Concentration yielded the sub-title compound (17.9 g; 80%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06255301B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-f7dc7d3fe3ee44b0bc12fb4eb26c4f42 |
| Source note | uspto-grants-2001_07 |