HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl 2-(3,5-dimethoxyphenyl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | (3,5-Dimethoxyphenyl)acetic acid | HCID 138316 | — |
| Product | Ethyl 2-(3,5-dimethoxyphenyl)acetate | HCID 11831071 | 88% |
Reaction Steps
A solution of 3,5-dimethoxyphenylacetic acid (2.0 g; 10 mmol) and H2SO4 (conc.; 0.2 mL) in EtOH (50 mL) was refluxed overnight. The solution was concentrated, and the resultant material was dissolved in aqueous NaOH (1M). After extraction with ether (2×75 mL), washing of the combined organic phase with brine, drying (Na2SO4) and evaporating, 2.0 g (88%) of the sub-title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06255301B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-9d499a4c79b14243a2a77ae77e2229ed |
| Source note | uspto-grants-2001_07 |