Putrescine → HCID 11065264, compound

HRID 1383389Notes

Reaction equation

HRID 1383389 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][NH2:6].[Cl:7][C:8]1[CH:13]=[CH:12][C:11]([S:14](Cl)(=[O:16])=[O:15])=[CH:10][CH:9]=1.C(Cl)(Cl)Cl>ClC=CCl>[Cl:7][C:8]1[CH:13]=[CH:12][C:11]([S:14]([NH:1][CH2:2][CH2:3][CH2:4][CH2:5][NH2:6])(=[O:16])=[O:15])=[CH:10][CH:9]=1

Participants

5

Reactant 3

HCID 1045PutrescineHCID 6212ChloroformHCID 73984-Chlorobenzenesulfonyl chloride

Product 1

HCID 11065264HCID 11065264, compoundYield 64,698.699%

Reagents, catalysts & solvents 1

HCID 109001,2-DichloroethyleneSolvent

Procedure

26.4 g (0.3 mol) of 1,4-diaminobutane was dissolved in 100 ml of 1,2-dichloroethene and stirred together with 6.3 g (0.03 mmol) of 4-chlorophenylsulfonyl chloride at room temperature for 4 hours. After addition of chloroform, the reaction solution was filtered through celite, and the filtrate was washed with water three times and with saturated aqueous sodium chloride successively, dried over anhydrous magnesium sulfate and evaporated in vacuo for removal of the solvent to give 5.1 g of the title compound in a yield of 65%.

Workup

  1. filtrationthe reaction solution was filtered through celite
  2. washthe filtrate was washed with water three times and with saturated aqueous sodium chloride successively
  3. dry with materialdried over anhydrous magnesium sulfate
  4. customevaporated in vacuo for removal of the solvent

Sources & evidence

ORD record
ord-96eec0f8c573411bab09c14d132f0d95
Source dataset
uspto-grants-2001_07
Patent number
US06255321B1

Reaction notes

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