Hydrazine hydrate (1:1) → HCID 178515940, compound

HRID 1383430Notes

Reaction equation

HRID 1383430 reaction equation
[C:1]1([C:7]2[O:8][C:9]3[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=3[C:11](=O)[N:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.O.[NH2:19][NH2:20]>C(O)C>[OH:8][C:9]1[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=1[C:11]1[N:12]=[C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[NH:20][N:19]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 5554072-Phenyl-4H-1,3-benzoxazin-4-one

Product 1

HCID 178515940HCID 178515940, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1.9 g of 2-phenyl-benzo[e][1,3]oxazin-4-one are refluxed in 75 ml of ethanol with 1.0 g of hydrazine hydrate. After about 1 hour the solvent is distilled off in vacuo and the residue remaining is stirred into water. The solid formed (3-(2-hydroxyphenyl)-5-phenyl-1,2,4-triazole) is used in the next step without further purification. Yield: 0.5 g (25%).

Workup

  1. distillationAfter about 1 hour the solvent is distilled off in vacuo

Sources & evidence

ORD record
ord-776f1199bbc141ab8448e95ac5998daa
Source dataset
uspto-grants-2001_07
Patent number
US06255327B1

Reaction notes

Loading…