HCID 21188002, compound → HCID 21187986, compound

Participants

Reaction Steps

0.7 g of 4-(2-benzyloxyphenyl)-2-phenyl-1,3-oxazole according to step (d) are hydrogenated in 30 ml of tetrahydrofuran in the presence of 0.1 g of Pd/C catalyst at 20-60° C. (5 bar). After the catalyst has been separated off the solvent is distilled off in vacuo and the residue remaining is chromatographed on silica gel (dioxane:hexane 1:5). Yield: 0.5 g (99%);

Provenance & Evidence