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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1383441Generated: October 30, 2026

HCID 21188020, compound → Phenol, 2-(2-phenyl-5-oxazolyl)-

https://huagongshe.com/reaction/1383441

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21188020HCID 21188020—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
ProductPhenol, 2-(2-phenyl-5-oxazolyl)-HCID 11128316—

Reaction Steps

0.55 g of 5-(2-benzyloxyphenyl)-2-phenyl-1,3-oxazole according to step (c) are hydrogenated in 30 ml of tetrahydrofuran in the presence of 0.1 g of Pd/C catalyst (10W) at about 60° C. (5.7 bar). After the catalyst has been separated off the solvent is distilled off in vacuo and the residue remaining is chromatographed on silica gel (dioxane:hexane 3:5).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06255327B1
Source datasetuspto-grants-2001_07
ORD IDord-2413310354814fb29d6a8830e629cc77
Source noteuspto-grants-2001_07