Thionyl Chloride → 3-Benzoyloxy-4-methoxybenzoylchloride

HRID 1383498ノート

反応式

HRID 1383498 の反応式
[C:1]([O:9][C:10]1[CH:11]=[C:12]([CH:16]=[CH:17][C:18]=1[O:19][CH3:20])[C:13](O)=[O:14])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:23])=O>C1(C)C=CC=CC=1>[C:1]([O:9][C:10]1[CH:11]=[C:12]([CH:16]=[CH:17][C:18]=1[O:19][CH3:20])[C:13]([Cl:23])=[O:14])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 211879403-Benzoyloxy-4-methoxybenzoic acid

生成物 1

HCID 211878683-Benzoyloxy-4-methoxybenzoylchloride

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

A solution of 3-benzoyloxy-4-methoxybenzoic acid (29.3 g; that is prepared as described in Reference Example 9) in toluene (300 mL) is treated with thionyl chloride (30 mL) and heated on the steam bath for 6 hours. It is then cooled, filtered and concentrated, to give 3-benzoyloxy-4-methoxybenzoyl chloride (28.7 g), m.p. 120-122° C.

後処理

  1. customthat is prepared
  2. temperatureheated on the steam bath for 6 hours
  3. temperatureIt is then cooled
  4. filtrationfiltered
  5. concentrationconcentrated

出典と根拠

ORDレコード
ord-6b6634ac129341dc883ad48766a21053
出典データセット
uspto-grants-2001_07
特許番号
US06255326B1

反応ノート

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