Sodium ion → 4-Methoxy-4-(4-pyrimidin-2-yl-phenyl)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[cH:15][cH:16][c:17](-[c:20]3[n:21][cH:22][cH:23][cH:24][n:25]3)[cH:18][cH:19]2)([OH:26])[CH2:12][CH2:13]1.[CH3:27][I:28].[H-:30].[Na+:29].[O:31]=[CH:32][N:33]([CH3:34])[CH3:35]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[cH:15][cH:16][c:17](-[c:20]3[n:21][cH:22][cH:23][cH:24][n:25]3)[cH:18][cH:19]2)([O:26][CH3:27])[CH2:12][CH2:13]1Participants
6
Sources & evidence
- ORD record
- ord-2138fb6260ac41faa6ce1548b7e55eb9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…