Water → HCID 21188061, compound

HRID 1383612Notes

Reaction equation

HRID 1383612 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[C:4]([Cl:12])[C:3]=1[N:13]1[CH:17]=[C:16]([C:18]#[C:19][Si](C)(C)C)[C:15]([CH3:24])=[N:14]1.C(=O)([O-])[O-].[K+].[K+].O>CO>[Cl:1][C:2]1[CH:7]=[C:6]([C:8]([F:9])([F:10])[F:11])[CH:5]=[C:4]([Cl:12])[C:3]=1[N:13]1[CH:17]=[C:16]([C:18]#[CH:19])[C:15]([CH3:24])=[N:14]1

Participants

5

Reactant 3

HCID 962WaterHCID 11430Potassium CarbonateHCID 21188102HCID 21188102, compound

Product 1

HCID 21188061HCID 21188061, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a stirred solution of 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-methyl4-trimethylsilylethynylpyrazole (0.82 g) in methanol (15 ml) was added potassium carbonate (0.75 g). After 3 hours at room temperature the reaction mixture was poured into water (100 ml) and extracted with ether (50 ml, ×2). The combined organic layers were washed with brine, dried and evaporated to provide the title compound as a light beige gum.

Workup

  1. extractionextracted with ether (50 ml, ×2)
  2. washThe combined organic layers were washed with brine
  3. customdried
  4. customevaporated

Sources & evidence

ORD record
ord-0e66bf7dc7f9470fa6179dc8e011f7bb
Source dataset
uspto-grants-2001_07
Patent number
US06255333B1

Reaction notes

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