反应详情

温度

110 °C

Acetic anhydride (23 ml) was heated to 110° C. and 2,6-lutidine-N-oxide (20 g) was added dropwise over 1 hour. The solution was heated at 110° C. for five hours. After cooling, the crude mixture was distilled to yield 2-acetoxymethyl-6-methylpyridine (18.4 g, b.p. 110-120° C. @ 15 mmHg).

1. temperatureAfter cooling
2. distillationthe crude mixture was distilled