HCID 20669247, compound → HCID 21189042, compound

HRID 1383868Notes

Reaction equation

HRID 1383868 reaction equation
[CH3:1][C:2]([C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][C:6]=1[OH:12])(O)[CH3:3]>C(OC(=O)C)(=O)C>[C:8]([O:12][C:6]1[CH:7]=[C:8]([O:11][C:6](=[O:12])[CH3:5])[CH:9]=[CH:10][C:5]=1[C:2]([CH3:3])=[CH2:1])(=[O:11])[CH3:7]

Participants

3

Reactant 1

HCID 20669247HCID 20669247, compound

Product 1

HCID 21189042HCID 21189042, compoundYield 142,299.406%

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

Compound (23) (1.7 g, 0.012 mmol) was dissolved in acetic anhydride (3.3 ml), and the solution was stirred for 30 minutes, and refluxed for four hours. The reaction solution was extracted with organic solvent, washed, dried and purified by using column chromatography (eluent: hexane/ethyl acetate=6/1), to obtain 2 g (85%) of pure compound (24).

Workup

  1. temperaturerefluxed for four hours
  2. extractionThe reaction solution was extracted with organic solvent
  3. washwashed
  4. customdried
  5. custompurified

Sources & evidence

ORD record
ord-2f3384a7a6404f9e863651b96984bf88
Source dataset
uspto-grants-2001_07
Patent number
US06255517B1

Reaction notes

Loading…