Hydrochloric Acid → HCID 10979791, compound

HRID 1383873Notes

Reaction equation

HRID 1383873 reaction equation
[CH3:1][O:2][C:3](=[O:22])[C:4](=[O:21])[C@@H:5]([NH:13][C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])[CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1.Cl>>[CH3:1][O:2][C:3](=[O:22])[C@@H:4]([OH:21])[C@@H:5]([NH:13][C:14]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:15])[CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 10063801HCID 10063801, compound

Product 1

HCID 10979791HCID 10979791, compound

Procedure

To the thus-prepared reducing agent was added 81.0 mg (0.26 mmol) of (3S)-[(t-butoxycarbonyl)amino]-2-oxo-4-phenylbutyric acid methyl ester, and the mixture was stirred at room temperature for 5 hours. After hydrolysis with 1 N hydrochloric acid, the reaction mixture was extracted with ethyl acetate.

Workup

  1. extractionthe reaction mixture was extracted with ethyl acetate

Sources & evidence

ORD record
ord-045c11dc69d040ada0b170dde446fcea
Source dataset
uspto-grants-2001_07
Patent number
US06255522B1

Reaction notes

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