1-Iodododecane → 3-[Dodecyl(methyl)amino]propan-1-OL

HRID 1383896Notes

Reaction equation

HRID 1383896 reaction equation
[CH3:1][NH:2][CH2:3][CH2:4][CH2:5][OH:6].I[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]>>[CH2:8]([N:2]([CH2:3][CH2:4][CH2:5][OH:6])[CH3:1])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 202821-IodododecaneHCID 101489863-(Methylamino)-1-propanol

Product 1

HCID 131222613-[Dodecyl(methyl)amino]propan-1-OLYield 96%

Procedure

A solution of 3-(methylamino)propanol (5.71 g, 64.0 mmol, S. Koepke, R. Kupper, and C. J. Michejda, J. Org. Chem., 44, 2718, 1979)), and iodododecane (7.58 g, 25.6 mmol) was reacted as described in example 1 to give 6.33 g (96%) of the title material as an oil, b.p. 100-105° C./0.04 torr.

Sources & evidence

ORD record
ord-1647560b948c4231a6a19d7216f8b6f6
Source dataset
uspto-grants-2001_07
Patent number
US06255496B1

Reaction notes

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