HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[4-[2-(N-dodecyl-N-methylamino)ethoxy]phenyl]1,1,1-trifluoro-2-butanone → 4-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-methoxyphenyl]-1,1,1-trifluoro-2-butanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[4-[2-(N-dodecyl-N-methylamino)ethoxy]phenyl]1,1,1-trifluoro-2-butanone | HCID 9955083 | — |
| Reactant | 3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-methoxyphenyl]propanoic acid, hydrochloride | HCID 131722759 | — |
| Product | 4-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-methoxyphenyl]-1,1,1-trifluoro-2-butanone | HCID 18319032 | 58% |
Reaction Steps
3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-methoxyphenyl]propanoic acid, hydrochloride (274 mg, 0.598 mmol) was reacted by the general procedure as described in the preparation of 4-[4-[2-(N-dodecyl-N-methylamino)- ethoxy]phenyl]-1,1,1-trifluoro-2-butanone and afforded the title compound (165 mg, 58%) as a pale yellow oil (b.p. 138-140° C./0.015 mmHg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06255496B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-a280238daedc4605a671dd4ccdd8e411 |
| Source note | uspto-grants-2001_07 |