Trifluoroacetic acid → HCID 18319061, compound
Reaction equation
CC([O:5][C:6](=[O:23])[CH2:7][O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][CH2:16][C:17](=[O:22])[C:18]([F:21])([F:20])[F:19])=[CH:11][CH:10]=1)(C)C.FC(F)(F)C(O)=O>>[F:19][C:18]([F:20])([F:21])[C:17](=[O:22])[CH2:16][CH2:15][C:12]1[CH:13]=[CH:14][C:9]([O:8][CH2:7][C:6]([OH:23])=[O:5])=[CH:10][CH:11]=1Participants
3
Procedure
4-(4,4,4-trifluoro-3-oxo-1-butyl)phenoxyacetic acid 1,1-dimethylethyl ester (0.450 g, 1.35 mmol) was treated with trifluoroacetic acid as described in example (133) to give 0.373 g (100%) of the material as a white solid.
Sources & evidence
- ORD record
- ord-c726bbcbf4234d51af78f54fcedf2f05
- Source dataset
- uspto-grants-2001_07
- Patent number
- US06255496B1
Reaction notes
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