2,4,6-Trimethylbenzoic acid → 2,4,6-Trimethylbenzoyl chloride

HRID 1384041Notes

Reaction equation

HRID 1384041 reaction equation
[CH3:1][C:2]1[CH:10]=[C:9]([CH3:11])[CH:8]=[C:7]([CH3:12])[C:3]=1[C:4](O)=[O:5].S(Cl)([Cl:15])=O>>[CH3:1][C:2]1[CH:10]=[C:9]([CH3:11])[CH:8]=[C:7]([CH3:12])[C:3]=1[C:4]([Cl:15])=[O:5]

Participants

3

Reactant 2

HCID 101942,4,6-Trimethylbenzoic acidHCID 24386Thionyl Chloride

Product 1

HCID 970382,4,6-Trimethylbenzoyl chloride

Procedure

A mixture of 328 mg of 2,4,6-trimethylbenzoic acid and 3 mL of thionyl chloride was stirred at room temperature for 2 hours. The volatile components were evaporate in vacuo, the residue was redissolved in 5 mL of CH2Cl2, and the volatile components were again evaporated in vacuo to give 2,4,6trimethylbenzoyl chloride.

Workup

  1. customThe volatile components were evaporate in vacuo
  2. dissolutionthe residue was redissolved in 5 mL of CH2Cl2
  3. customthe volatile components were again evaporated in vacuo

Sources & evidence

ORD record
ord-8c90d1a690bc489b95d3020c69727a24
Source dataset
uspto-grants-2001_07
Patent number
US06258360B1

Reaction notes

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