HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 70182737, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 70183438 | HCID 70183438 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 70182737 | HCID 70182737 | — |
Reaction Steps
A solution of the product of Example 11 (690 mg, 1.8 mmol) and sodium hydroxide (285 mg) in THF (20 ml) is refluxed for 8 h, acidified to pH 1 (concentrated HCl), extracted with ethyl acetate and washed with water. After drying, the organic phase is concentrated on a rotary evaporator under vacuum at 40° C. and the product is washed with heptane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06258775B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-01e946391f7f4ed881e25bb79e873dd9 |
| Source note | uspto-grants-2001_07 |