2-Butenoic acid, 3-amino-, ethyl ester, (2Z)- → HCID 21186750, compound

Participants

Reaction Steps

2-Formylcycloheptanone (1.70 g, 12.1 mmol) and ethyl 3-aminocrotonate (1.58 g, 12.1 mmol) were stirred at 100° C. for 15 hours. After cooling, the reaction solution was purified by a silica gel column chromatography (ether/hexane=1:3) to obtain the title compound (1.35 g, 46.1%) as pale yellow powder.

Provenance & Evidence