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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 138452Generated: October 27, 2026

Dimethylformamide → (9-(3-Fluoro-5-(2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-isopropylthiazol-5-yl)methanone

https://huagongshe.com/reaction/138452

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantHexafluorophosphateHCID 9886—
Reactant(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 4641409—
Reactant2-(Propan-2-yl)-1,3-thiazole-5-carboxylic acidHCID 19786342—
Reactant2-(3-(1-Oxa-4,9-diazaspiro[5.5]undecan-9-ylmethyl)-5-fluorophenyl)ethanolHCID 57988990—
Product(9-(3-Fluoro-5-(2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-isopropylthiazol-5-yl)methanoneHCID 57988964—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-3c0c09d560434b449dc236eb20e171f3
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)