Dichloromethane → Trifluoroacetic acid

HRID 138476Notes

Reaction equation

HRID 138476 reaction equation
[C:1]([c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1)(=[O:8])[NH:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][NH:15][C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22].[Cl:30][CH2:31][Cl:32].[F:23][C:24]([C:25](=[O:26])[OH:27])([F:28])[F:29]>>[C:1]([c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1)(=[O:8])[NH:9][CH2:10][CH2:11][O:12][CH2:13][CH2:14][NH2:15].[F:23][C:24]([C:25](=[O:26])[OH:27])([F:28])[F:29]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 69811586Tert-butyl 2-(2-(nicotinamido)ethoxy)ethylcarbamate

Product 2

HCID 6422Trifluoroacetic acidHCID 58173191N-[2-(2-Aminoethoxy)ethyl]-3-pyridinecarboxamide

Sources & evidence

ORD record
ord-a9e0a97bf3b2467f85405615915ef9a7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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