HCID 14039945, compound → HCID 14039941, compound

HRID 1384879Notes

Reaction equation

HRID 1384879 reaction equation
[OH:1][C:2]1[C:15]2[CH2:14][CH2:13][C@H:12]3[C@H:7]([CH2:8][CH2:9][CH2:10][N:11]3[CH2:16][CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[C:6]=2[CH:5]=[CH:4][CH:3]=1>CO>[OH:1][C:2]1[C:15]2[CH2:14][CH2:13][CH:12]3[CH:7]([CH2:8][CH2:9][CH2:10][N:11]3[CH2:16][CH2:17][C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=3)[C:6]=2[CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 1

HCID 14039945HCID 14039945, compound

Product 1

HCID 14039941HCID 14039941, compoundYield 50%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Cis-(+)-7-hydroxy-4-phenethyl-1,2,3,4,4a,5,6, 10b-octahydrobenzo[f]quinoline (hereinafter, “cis-(+)-25”) was prepared in 50% yield from 37 mg (0.12 mmole) of cis-(+)-24 by the method of forming trans-9 as described in Example 3. The melting point observed was 194° C. and [α]D (20° C.) was +6.05 (c 0.22, MeOH).

Workup

  1. customof forming trans-9
  2. customobserved was 194° C.

Sources & evidence

ORD record
ord-2580bcba933848728bd95dd17d93f62d
Source dataset
uspto-grants-2001_07
Patent number
US06262064B1

Reaction notes

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