HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline → HCID 21183923, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline | HCID 616267 | — |
| Reactant | 5-Methylisoxazole-3-carbonyl chloride | HCID 2736894 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 21183923 | HCID 21183923 | — |
Reaction Steps
A solution of 5-methylisoxazole-3-carbonyl chloride (0.41 g., 2.83 mmole) in dioxane was added to a solution of 4-amino-6,7-dimethoxy-2-(1-piperazinyl)quinazoline (0.82 g., 2.83 mmole) in dioxane. The mixture was treated as described in the previous example to give the title compound having a m.p. of 271°-273° C. with decomposition.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06262059B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-5ad027bbdee6488d851fbfc3f88ada10 |
| Source note | uspto-grants-2001_07 |