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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1385073Generated: October 31, 2026

Bromine → 1-Acetyl-5-bromo-2,3-dihydro-3-[2-(methanesulphonyl)ethyl]-1h-indole

https://huagongshe.com/reaction/1385073

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromineHCID 24408—
Reactant1-Acetyl-2,3-dihydro-3-[2-(methanesulphonyl)ethyl]-1H-indoleHCID 18545886—
SolventAcetic AcidHCID 176—
SolventDichloromethaneHCID 6344—
Product1-Acetyl-5-bromo-2,3-dihydro-3-[2-(methanesulphonyl)ethyl]-1h-indoleHCID 18545809—

Reaction Steps

Bromination was done by treatment of 19a with bromine in a mixture of acetic acid and dichloromethane. The compound was an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06262087B1
Source datasetuspto-grants-2001_07
ORD IDord-036d1b2a1306441cba02e701b057890d
Source noteuspto-grants-2001_07