3-Bromocyclohexene → HCID 54264252, compound

HRID 1385108Notes

Reaction equation

HRID 1385108 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([C:9]([CH2:14][CH3:15])=[N:10][NH:11]2)=[CH:7][CH:6]=1)=[O:4].Br[CH:17]1[CH2:22][CH2:21][CH2:20][CH:19]=[CH:18]1>>[CH3:1][O:2][C:3]([C:5]1[CH:13]=[C:12]2[C:8]([C:9]([CH2:14][CH3:15])=[N:10][N:11]2[CH:22]2[CH2:21][CH2:20][CH2:19][CH:18]=[CH:17]2)=[CH:7][CH:6]=1)=[O:4]

Participants

3

Reactant 2

HCID 1370573-BromocyclohexeneHCID 178438014HCID 178438014, compound

Product 1

HCID 54264252HCID 54264252, compoundYield 45%

Procedure

This compound was prepared according to the method of Preparation 1, using 750 mg (3.67 mmol, 1.0 equiv) 3-ethyl-1H-indazole-6-carboxylic acid methyl ester and 0.46 mL (4.04 mmol, 1.1 equiv) 3-bromocyclohexene as starting materials to give 467 mg (45%) of a clear oil: HRMS calcd for C27H20N2O2: 284.1525. Found: 284.1512.

Workup

  1. customThis compound was prepared
  2. customaccording to the method of Preparation 1

Sources & evidence

ORD record
ord-e684de9c4a8245b79245a3f1f50ff260
Source dataset
uspto-grants-2001_07
Patent number
US06262040B1

Reaction notes

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