Sodium Azide → HCID 21716276, compound

HRID 1385897Notes

Reaction equation

HRID 1385897 reaction equation
CS(O[CH:6]1[CH2:15][CH2:14][C:13]2[C:8](=[CH:9][CH:10]=[C:11]([O:16][CH3:17])[CH:12]=2)[CH2:7]1)(=O)=O.[N-:18]=[N+:19]=[N-:20].[Na+]>CN(C=O)C.CCOCC>[N:18]([CH:6]1[CH2:15][CH2:14][C:13]2[C:8](=[CH:9][CH:10]=[C:11]([O:16][CH3:17])[CH:12]=2)[CH2:7]1)=[N+:19]=[N-:20]

Participants

5

Reactant 2

HCID 33557Sodium AzideHCID 21716273HCID 21716273, compound

Product 1

HCID 21716276HCID 21716276, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6228DimethylformamideSolvent

Procedure

8.0 g (31 mmol) of 2-methanesulfonyloxy-6-methoxytetralin and 2.6 g (40 mmol) of sodium azide were heated for 3 hours at 90° C. in 100 ml of DMF. After the mixture had been cooled, it was diluted with ether, washed with water and saturated NaCl solution, dried and concentrated in vacuo. This gave 6 g (95% of theory) of a colorless oil which was further reacted directly.

Workup

  1. temperatureAfter the mixture had been cooled
  2. washwashed with water and saturated NaCl solution
  3. customdried
  4. concentrationconcentrated in vacuo
  5. customThis gave 6 g (95% of theory) of a colorless oil which was further reacted directly

Sources & evidence

ORD record
ord-29958859fe404cdb80a35f8c007b2fe5
Source dataset
uspto-grants-2001_07
Patent number
US06265398B1

Reaction notes

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