Triethylamine → 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride

Participants

Reaction Steps

Prepared according to the method described in Example 10, from N-boc-1,6-diamino-hexane hydrochloride (0.202 g), 1-hydroxybenzotriazole hydrate (0.065 g), triethylamine (0.11 ml), (2R)-1-[2-(6-(3-propanoic acid)naphthyloxy]-4-(3-pyridyl)-2-butanol (0.147 g, Example 9), dry N,N-dimethylformamide (20 ml) and 1-ethyl-3-(3′-dimethylaminopropyl)carbodiimide hydrochloride (0.092 g) to give the title compound as a pale yellow solid (0.116 g).

Provenance & Evidence