4-Methylpiperidine → HCID 21717156, compound

HRID 1386027Notes

Reaction equation

Cl[CH2:2][CH2:3][CH:4]1[CH2:9][S:8][CH2:7][CH2:6][N:5]1[S:10]([C:13]1[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[CH:15][CH:14]=1)(=[O:12])=[O:11].[CH3:23][CH:24]1[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1>>[CH3:23][CH:24]1[CH2:29][CH2:28][N:27]([CH2:2][CH2:3][CH:4]2[CH2:9][S:8][CH2:7][CH2:6][N:5]2[S:10]([C:13]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH:16]=[CH:15][CH:14]=2)(=[O:12])=[O:11])[CH2:26][CH2:25]1

Participants

Reactant 2

HCID 693814-Methylpiperidine

HCID 21717142HCID 21717142, compound

Product 1

HCID 21717156HCID 21717156, compoundYield 63%

Procedure

The title compound (250 mg, 63%) was prepared according to the procedure outlined in Examples 5-44 using 3-(2-chloroethyl)-4-(naphthalene-1-sulfonyl)thiomorpholine and 4-methylpiperidine. MH+ 419.

Sources & evidence

ORD record: ord-22aa24a8a20347e28328f8a2939f7454
Source dataset: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06265408B1

Reaction notes

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