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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1386672Generated: November 1, 2026

HCID 178452156, compound → HCID 178515850, compound

https://huagongshe.com/reaction/1386672

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178452156HCID 178452156—
SolventHydrochloric AcidHCID 313—
SolventMethanolHCID 887—
ProductHCID 178515850HCID 178515850—

Reaction Steps

A solution of 105 mg (0.27 mmol) of 1-t-butoxycarbonyl-4-hydroxy-4-(3-(4-(1H-tetrazol-5-yl)phenyl)-propyl)piperidine (from EXAMPLE 2, Step E) in 5 mL of 0.5 N HCl in MeOH was stirred at rt for 20 h. The solution was concentrated and dried under vacuum to afford the title compound: HPLC B: 3.10 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06265434B1
Source datasetuspto-grants-2001_07
ORD IDord-df621917ffdb477cb2ceef702e743c6f
Source noteuspto-grants-2001_07