HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178452156, compound → HCID 178515850, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178452156 | HCID 178452156 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178515850 | HCID 178515850 | — |
Reaction Steps
A solution of 105 mg (0.27 mmol) of 1-t-butoxycarbonyl-4-hydroxy-4-(3-(4-(1H-tetrazol-5-yl)phenyl)-propyl)piperidine (from EXAMPLE 2, Step E) in 5 mL of 0.5 N HCl in MeOH was stirred at rt for 20 h. The solution was concentrated and dried under vacuum to afford the title compound: HPLC B: 3.10 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06265434B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-df621917ffdb477cb2ceef702e743c6f |
| Source note | uspto-grants-2001_07 |