HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 21180662, compound → 2-(R)-(3-(S)-((4-(2,2-Dimethyl-3-phenylpropyl)piperidin-1-yl)methyl)-4-(S)-phenylpyrrolidin-1-yl)-2-(cyclohexyl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 21180662 | HCID 21180662 | — |
| Reactant | alpha-(R)-(3-(R)-formyl-4-(S)-phenylpyrrolidin-1-yl)-cyclohexaneacetic acid 4-methoxybenzyl ester | HCID 53654320 | — |
| Product | 2-(R)-(3-(S)-((4-(2,2-Dimethyl-3-phenylpropyl)piperidin-1-yl)methyl)-4-(S)-phenylpyrrolidin-1-yl)-2-(cyclohexyl)acetic acid | HCID 20672336 | — |
Reaction Steps
The title compound was prepared from 9 mg (0.05 mmol) of 4-(3-phenyl-2,2-dimethylpropyl)piperidine (from EXAMPLE 98, Step I) and 20 mg (0.05 mmol) of 2-(R)-(3-(R)-formyl-4-(S)-phenylpyrrolidin-1-yl)-2-(cyclohexyl)acetic acid, 4-methoxybenzyl ester (from EXAMPLE 33, Step E) using procedures analogous to those described in EXAMPLE 1, Step J and EXAMPLE 10, Step F. For the title compound: ESI-MS 531 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06265434B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-37bcc8749e114e34a8c330d37034b0b5 |
| Source note | uspto-grants-2001_07 |