HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Benzyloxycarbonyl)-4-(3-oxo-3-phenylprop-1-enyl)piperidine → 1-(Benzyloxycarbonyl)-4-(3-oxo-3-phenylpropyl)piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Benzyloxycarbonyl)-4-(3-oxo-3-phenylprop-1-enyl)piperidine | HCID 57074489 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(Benzyloxycarbonyl)-4-(3-oxo-3-phenylpropyl)piperidine | HCID 18187454 | 100.1% |
Reaction Steps
1-(Benzyloxycarbonyl)-4-(3-oxo-3-phenylprop-1-enyl)piperidine (0.95 g, 2.7 mmol, from EXAMPLE 154, Step A) was hydrogenated using 5% Pd/C (10 mg) in 95% ethanol (20 mL) at atmospheric pressure. After 3.5 h, the mixture was filtered and the catalyst was washed with 95% ethanol. Evaporation of the filtrate gave 0.95 g of 1-(benzyloxycarbonyl)-4-(3-oxo-3-phenylpropyl)piperidine as a colorless syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06265434B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-e18aafbc93e846b4bd1a7bdeb3c36a10 |
| Source note | uspto-grants-2001_07 |