HCID 131722813, compound → HCID 54467862, compound

Participants

Reaction Steps

To a solution of 1 g of ((1-benzyl)piperidin-4-ylidene)acetic acid, t-butyl ester (from EXAMPLE 163, Step A) in 10 mL of EtOH was added 100 mg of platinum oxide at rt. The solution was hydrogenated for 3 h under one atmosphere of hydrogen gas. After filtering through celite, the filtrate was concentrated under reduced pressure to give 936 mg of the title compound as a viscous oil.

Provenance & Evidence