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HRID1386869

反应详情

EQUATION

反应方程式

HRID 1386869 的结构方程式

REACTANTS

反应物

4
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：C=O
HCID712

Formaldehyde

CH2O

结构：OP(O)O
HCID107909

Phosphorous acid

H3O3P

结构：CC(=O)N(C)CC(=O)O
HCID10975514

N-acetyl-N-methylglycine

C5H9NO3

PRODUCTS

生成物

1
结构：CN(CC(=O)O)CP(=O)(O)O
HCID541499

N-methyl-N-(phosphonomethyl)glycine

C4H10NO5P

收率 99%

CONDITIONS

反应条件

温度
120 °C

PROCEDURE

实验过程

N-acetyl sarcosine (XX) (20.0 g, 152.5 mmole), phosphorous acid (12.5g, 152.4 mmole), and concentrated HCl (37.6 g) were mixed and refluxed in a 120° C. oil bath. Formalin, 37% (13.6 g, 167.6 mmole) was added dropwise over 20 min. and the reaction was continued for an additional 19 h. HPLC analysis indicated a 99% yield of N-methylglyphosate (XXI) based on moles of (XX) charged.