HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 69829296, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 69829960 | HCID 69829960 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 69829296 | HCID 69829296 | 99% |
Reaction Steps
A solution of 4-tert-butoxycarbonylmethoxy-3-fluoro-benzoic acid methyl ester in CH2Cl2 was treated with trifluoroacetic acid (14.9 ml, 130 mmol, 10.6 eq.) (20 ml) for 3.5 hrs. at r.t. Following evaporation to dryness, the title compound (2.77 g, 99% yield) was obtained as an off-white solid. MS: m/e=228 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06265426B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-316cf81f27b4497bbc1b0d68bf1cda83 |
| Source note | uspto-grants-2001_07 |