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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1387022Generated: October 26, 2026

3,4-Difluorobenzoyl chloride → 6-Benzyloxy-2-(dimethylamino)benzo[b]thiophen-3-yl 3,4-Difluorophenyl Ketone

https://huagongshe.com/reaction/1387022

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Difluorobenzoyl chlorideHCID 2724519—
Reactant6-Benzyloxy-2-dimethylaminobenzo[b]thiopheneHCID 10612994—
Product6-Benzyloxy-2-(dimethylamino)benzo[b]thiophen-3-yl 3,4-Difluorophenyl KetoneHCID 2118262395%

Reaction Steps

The title compound (oil) was prepared in 95% yield from 6-benzyloxy-2-(dimethylamino)benzo[b]thiophene and 3,4-difluorobenzoyl chloride by essentially following the procedure outlined in Example 81, Part C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06265575B1
Source datasetuspto-grants-2001_07
ORD IDord-185ede9e4dc54d719e43e0352b76d413
Source noteuspto-grants-2001_07