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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1387039Generated: October 30, 2026

6-Allyloxy-2-(dimethylamino)benzo[b]thiophene → 6-Allyloxy-2-(dimethylamino)benzo[b]thiophen-3-yl 4-(Dimethylamino)methyl-3-methoxyphenyl Ketone

https://huagongshe.com/reaction/1387039

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Allyloxy-2-(dimethylamino)benzo[b]thiopheneHCID 21182735—
Reactant4-Dimethylaminomethyl-3-methoxy-benzoic acidHCID 21182890—
Product6-Allyloxy-2-(dimethylamino)benzo[b]thiophen-3-yl 4-(Dimethylamino)methyl-3-methoxyphenyl KetoneHCID 2118276673%

Reaction Steps

The title compound was prepared in 73% yield (23% SM recovered) by essentially following the procedures outlined in Example 84, Part A from 6-allyloxy-2-(dimethylamino)benzo[b]thiophene (Part B) and 4-(dimethylamino)methyl-3-methoxybenzoic acid (Part D).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06265575B1
Source datasetuspto-grants-2001_07
ORD IDord-0571af7749194955ac52f32a1dce86ae
Source noteuspto-grants-2001_07