Pyrrolidine → HCID 21182790, compound

HRID 1387053Notes

Reaction equation

[NH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.Br[CH:7]([CH2:13][CH3:14])[C:8](OCC)=[O:9]>>[N:1]1([CH:7]([CH2:13][CH3:14])[CH2:8][OH:9])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

Reactant 2

HCID 31268Pyrrolidine

HCID 79039Butanoic acid, 2-bromo-, ethyl ester

Product 1

HCID 21182790HCID 21182790, compoundYield 64%

Procedure

The title compound was prepared in 64% yield for 2 steps from pyrrolidine and ethyl 2-bromobutyrate by essentially following the procedure detailed in Example 121, Part A.

Sources & evidence

ORD record: ord-92004ad25b5c47fb9b590d05a3d40284
Source dataset: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06265575B1

Reaction notes

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