HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-4-methoxybenzanilide → 3-[3-(3-Nitrophenyl)-thioureido]-4-methoxy-N-phenyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-4-methoxybenzanilide | HCID 8426 | — |
| Reactant | Benzene, 1-isothiocyanato-3-nitro- | HCID 19050 | — |
| Product | 3-[3-(3-Nitrophenyl)-thioureido]-4-methoxy-N-phenyl-benzamide | HCID 10477320 | 87.6% |
Reaction Steps
Prepared according to the procedure described for Example 60 using 3-amino-4-methoxy-N-phenyl-benzamide (0.243 g, 1.0 mmol) and 3-nitrophenyl isothiocyanate (0.183 g, 1.0 mmol). Trituration in hexanes/ethyl acetate (4:1) gave the product (0.370 g); m.p. 188-189° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06268387B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-9cf7668fae0543758425849fd9fde2df |
| Source note | uspto-grants-2001_07 |