4-Toluenesulfonyl chloride → HCID 18626220, compound

HRID 1387573Notes

Reaction equation

HRID 1387573 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](Cl)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[NH2:12][C:13]1[CH:14]=[C:15]([CH:25]=[CH:26][C:27]=1[O:28][CH3:29])[C:16]([NH:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)=[O:17]>>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([NH:12][C:13]2[CH:14]=[C:15]([CH:25]=[CH:26][C:27]=2[O:28][CH3:29])[C:16]([NH:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[O:17])(=[O:10])=[O:9])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 73974-Toluenesulfonyl chlorideHCID 84263-Amino-4-methoxybenzanilide

Product 1

HCID 18626220HCID 18626220, compoundYield 77%

Procedure

Prepared according to the procedure described for Example 121 using 4-methylbenzenesulfonyl chloride (2.06 g, 10 mmol) and 3-amino-4-methoxy-N-phenyl-benzamide (2.43 g, 10.0 mmol) to afford the product (3.053 g); m.p. 200-202° C.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-96811f214a564148abd4011b39a2c260
Source dataset
uspto-grants-2001_07
Patent number
US06268387B1

Reaction notes

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