3-Amino-4-methoxybenzanilide → HCID 18626110, compound

HRID 1387581Notes

Reaction equation

HRID 1387581 reaction equation
[CH2:1]([S:3](Cl)(=[O:5])=[O:4])[CH3:2].[NH2:7][C:8]1[CH:9]=[C:10]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[C:11]([NH:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:12]>N1C=CC=CC=1>[CH2:1]([S:3]([NH:7][C:8]1[CH:9]=[C:10]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[C:11]([NH:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)=[O:12])(=[O:5])=[O:4])[CH3:2]

Participants

4

Reactant 2

HCID 84263-Amino-4-methoxybenzanilideHCID 11667Ethanesulfonyl chloride

Product 1

HCID 18626110HCID 18626110, compoundYield 90.4%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Prepared according to the procedure described for Example 121 using ethanesulfonyl chloride (1.5 mL, 15.8 mmol), 3-amino-4-methoxy-N-phenyl-benzamide (2.43 g. 10 mmol) and pyridine (25 mL) to afford the product (3.023 g); m.p. 175-177° C. after trituration in hexanes/ethyl acetate (1:1).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-69b02c00af5744fa85f864cdafae11a8
Source dataset
uspto-grants-2001_07
Patent number
US06268387B1

Reaction notes

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