Dichlorodimethylsilane → HCID 17917429, compound

HRID 1387666Notes

Reaction equation

HRID 1387666 reaction equation
[N:1]1([C:6]2([Li])[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[CH:8]=[CH:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[Si:16](Cl)([Cl:19])([CH3:18])[CH3:17]>C1COCC1>[Cl:19][Si:16]([CH3:18])([CH3:17])[CH:8]1[C:9]2[C:14](=[CH:13][CH:12]=[CH:11][CH:10]=2)[C:6]([N:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)=[CH:7]1

Participants

4

Reactant 2

HCID 6398DichlorodimethylsilaneHCID 178506773HCID 178506773, compound

Product 1

HCID 17917429HCID 17917429, compoundYield 82%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

A solution of (1-(1-pyrrolidinyl)-1H-indenyl)lithium (2.0) g. 10.46 mmol) in 25 mL of THF was added within 30 minutes to a 50 mL THF solution containing SiMe2Cl2 (8.1 g, 62.76 mmol). After the addition was complete the reaction mixture was stirred overnight. The solvent was then removed under reduced pressure. The residue was extracted with hexane and the solution was filtered. The solvent was then removed under reduced pressure leaving 2.40 g of product. Yield 82 percent.

Workup

  1. additionAfter the addition
  2. customThe solvent was then removed under reduced pressure
  3. extractionThe residue was extracted with hexane
  4. filtrationthe solution was filtered
  5. customThe solvent was then removed under reduced pressure

Sources & evidence

ORD record
ord-30f7c3b7709f47f9aae1ec70e80fdef5
Source dataset
uspto-grants-2001_07
Patent number
US06268444B1

Reaction notes

Loading…