Hydrochloric Acid → HCID 11731087, compound

HRID 1387746Notes

Reaction equation

HRID 1387746 reaction equation
C(OC([N:8]1[CH2:13][C@@H:12]([O:14][CH2:15][CH3:16])[C@H:11]([C:17]2[CH:22]=[CH:21][C:20]([O:23][CH2:24][CH2:25][CH2:26][O:27][CH2:28][C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)=[CH:19][CH:18]=2)[C@@H:10]([O:35][CH2:36][C:37]2[CH:46]=[CH:45][C:44]3[C:39](=[CH:40][CH:41]=[CH:42][CH:43]=3)[CH:38]=2)[CH2:9]1)=O)(C)(C)C.Cl>>[CH2:28]([O:27][CH2:26][CH2:25][CH2:24][O:23][C:20]1[CH:19]=[CH:18][C:17]([C@H:11]2[C@H:12]([O:14][CH2:15][CH3:16])[CH2:13][NH:8][CH2:9][C@@H:10]2[O:35][CH2:36][C:37]2[CH:46]=[CH:45][C:44]3[C:39](=[CH:40][CH:41]=[CH:42][CH:43]=3)[CH:38]=2)=[CH:22][CH:21]=1)[C:29]1[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 11331057HCID 11331057, compound

Product 1

HCID 11731087HCID 11731087, compound

Procedure

reacting the product of step g) with hydrochloric acid to yield (3R,4S,5S)-4-[4-(3-benzyloxy-propoxy)-phenyl]-5-ethoxy-3-(naphthalen-2-ylmethoxy)-piperidine.

Sources & evidence

ORD record
ord-7b9a1d5eba7b45f1b1fc30c3d1468d0e
Source dataset
uspto-grants-2001_07
Patent number
US06268499B1

Reaction notes

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