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To a mixture of 3-bromobenzaldehyde (10 g) and methoxy-carbonylmethylenetriphenylphosphine (20 g) was added toluene (150 ml), and the mixture was refluxed under nitrogen atmosphere for 2 hours. The solvent was evaporated, and the organic layer was washed with water and saturated sodium chloride solution, and dried with anhydrous magnesium sulfate. Under reduced pressure, the solvent was evaporated, and the residue was purified with silica gel column (ethyl acetate/hexane) to give methyl 3-bromocinnamate (10.7 g) as colorless crystals. 1H-NMR(δ ppm, CDCl3): 3.82 (3H, s), 6.44 (1H, d, J=16.0 Hz),

1. temperaturethe mixture was refluxed under nitrogen atmosphere for 2 hours
2. customThe solvent was evaporated
3. washthe organic layer was washed with water and saturated sodium chloride solution
4. dry with materialdried with anhydrous magnesium sulfate
5. customUnder reduced pressure, the solvent was evaporated
6. customthe residue was purified with silica gel column (ethyl acetate/hexane)