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HRID1388081

反应详情

EQUATION

反应方程式

HRID 1388081 的结构方程式

REACTANTS

反应物

2
结构：CN=C=O
HCID12228

Methyl isocyanate

C2H3NO

结构：CCC(CC)Nc1c([N+](=O)[O-])cc(C)c(CO)c1[N+](=O)[O-]
HCID156688

3-((1-Ethylpropyl)amino)-6-methyl-2,4-dinitrobenzyl alcohol

C13H19N3O5

PRODUCTS

生成物

1
结构：CCC(CC)Nc1c([N+](=O)[O-])cc(C)c(COC(=O)NC)c1[N+](=O)[O-]
HCID12940769

未命名化合物

收率 91.6%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CCN(CC)CC
催化剂HCID8471

Triethylamine

C6H15N

结构：c1ccccc1
溶剂HCID241

Benzene

C6H6

PROCEDURE

实验过程

A mixture of 3-[(1-ethylpropyl)amino]-6-methyl-2,4-dinitrobenzyl alcohol (1.0 g; 0.0033 mol), methyl isocyanate (used in excess over theory), triethylamine (1 drop) and benzene (10 ml) is refluxed for 2 hours. The precipitated solid is collected to afford 1.1 g (91.6%) title product, melting point 117°-120° C.

WORKUP

后处理

  1. temperatureis refluxed for 2 hours
  2. customThe precipitated solid is collected